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AMPLITUDE

A Study to evaluate the efficacy and safety of VX-147 in Subjects with APOL1-mediated Proteinuric Kidney Disease

Chronic kidney disease, Nephropathy, Proteinuria

All genders

18-65

Recruiting now

Department of Medicine, Division of Nephrology

Tufts Medical Center

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Cardiovascular Biorepository

Cardiovascular Tissue and DNA Banking Study

Cardiovascular diseases

All genders

No minimum age

Recruiting now

CardioVascular Center

Tufts Medical Center

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FACT-CRT

Factors Associated with Response to Cardiac Resynchronization Therapy in Heart Failure Patients with Non-LBBB ECG Pattern

Cardiac failure, Heart failure

All genders

18+

Recruiting now

CardioVascular Center

Tufts Medical Center

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Acute Hemodynamics in Patients on AMCS

Cardiac arrest, Cardiac failure

All genders

18+

Recruiting now

CardioVascular Center

Tufts Medical Center

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NRG-BN009

Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse After Upfront SRS With Brain Metastasis Velocity ≥4 Brain Metastases/Year

Brain cancer

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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CATALYST Trial

Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants

Atrial fibrillation

All genders

18+

Recruiting now

CardioVascular Center

Tufts Medical Center

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A Study of Daratumumab-Based Therapies

A Phase 2, Multicohort Study of Daratumumab-Based Therapies in Participants with Amyloid Light Chain (AL) Amyloidosis

Amyloidosis

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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A Study of the Pharmacokinetics, Safety, and Efficacy of ASTX727

ASTX727-07 - A Single-Arm, Open-Label Pharmacokinetic, Safety, and Efficacy Study of ASTX727 in Combination with Venetoclax in Adult Patients with Acute Myeloid Leukemia

Acute myeloid leukemia (AML)

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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PBCAR0191

Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate Safety and Clinical Activity of PBCAR0191 in Subjects With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

All genders

18+

Recruiting now

Department of Medicine, Division of Hematology/Oncology, Cancer Center

Tufts Medical Center

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TREO Post Approval Study

Post-Approval Study of the TREO Abdominal Stent-Graft System in Patients with Infrarenal Abdominal Aortic and Aorto-iliac Aneurysms

Abdominal aortic aneurysm, Aortic aneurysm

All genders

18+

Recruiting now

Department of Surgery

Tufts Medical Center

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A Study to evaluate the efficacy and safety of VX-147 in Subjects with APOL1-mediated Proteinuric Kidney Disease

Cardiovascular Tissue and DNA Banking Study

Factors Associated with Response to Cardiac Resynchronization Therapy in Heart Failure Patients with Non-LBBB ECG Pattern

Acute Hemodynamics in Patients on AMCS

Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse After Upfront SRS With Brain Metastasis Velocity ≥4 Brain Metastases/Year

Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants

A Phase 2, Multicohort Study of Daratumumab-Based Therapies in Participants with Amyloid Light Chain (AL) Amyloidosis

ASTX727-07 - A Single-Arm, Open-Label Pharmacokinetic, Safety, and Efficacy Study of ASTX727 in Combination with Venetoclax in Adult Patients with Acute Myeloid Leukemia

Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate Safety and Clinical Activity of PBCAR0191 in Subjects With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Post-Approval Study of the TREO Abdominal Stent-Graft System in Patients with Infrarenal Abdominal Aortic and Aorto-iliac Aneurysms