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Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)



Kidney disease is a worldwide public health problem, disproportionately affecting older people and lower and middle-income countries, with major outcomes including kidney failure and cardiovascular disease. The CKD Epidemiology Collaboration (CKD-EPI) is a research group with interests in the measurement and estimation of GFR (CKD-EPI GFR) and evaluation of surrogate endpoints for clinical trials in CKD (CKD-EPI CT). CKD-EPI was founded by Dr. Andrew S. Levey, who served as Director from  2004 to 2018 and continues to serve as co-director. Dr. Lesley A. Inker has been the Director of the Data Coordinating Center since 2004 and co-director since 2018.


GFR estimation (CKD-EPI GFR)

The Steering Committee guides the overall direction and policies and is co-chaired by Drs. Lesley A. Inker, and Andrew S. Levey. Drs. Josef Coresh and Tom Greene are members of the committee. The Data Coordination Center is at Tufts Medical Center under the direction of Dr. Inker, and the Central Laboratory is at the University of Minnesota. Dr. Amy Karger has been serving as the Director since 2015. Dr. John Eckfeldt was the previous Director of the Central Laboratory. 

Surrogate endpoints for clinical trials (CKD-EP CT)

The Steering Committee guides the overall direction and policies and is chaired by Dr. Lesley A. Inker.  The committee will consist of permanent members, one representative of the CKD-Prognosis Consortium, and up to four rotating members. 

Permanent members are Drs. Inker, Tom Greene, Hiddo  L. Heerspink and Andrew S. Levey. CKD-PC representative will be decided upon by CKD-PC. Josef Coresh will be the initial representative. Rotating members will rotate every two years and will consist of two collaborators and up to two stakeholders. The Data Coordinating Center is at Tufts Medical Center, under the direction of Dr. Inker. The statistical center is at the University of Utah under the direction of Dr. Greene. Randomized Clinical Trials Identification and Acquisition Center is at Groningen University under the direction of Dr. Heerspink.

Organization and policy documents

Click here to download the CKD-EPI GFR organization and policy document.
Click here for CKD-EPI CT.

Contact Info
Division of Nephrology
Tufts Medical Center
800 Washington St.
Boston, MA 02111
Epidemiology collaboration physicians and students
Ckd-epi speaker
Chronic Kidney Disease physicians
CKD-EPI faculty
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